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Bergland Devil's Claw Cream 200 ml

£9.9£99Clearance
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Romiti N, Tramonti G, Corti A, Chieli E. Effects of Devil's Claw (Harpagophytum procumbens) on the multidrug transporter ABCB1/P-glycoprotein. Phytomedicine 2009;16:1095-100. View abstract. A study published in the journal Phytomedicine in 2002 found that patients with hip or knee arthritis taking a supplement containing devil’s claw over eight weeks saw a 54% and 39% improvement respectively in their pain levels. 11 Summary Occhiuto, F., Circosta, C., Ragusa, S., Ficarra, P., and Costa, De Pasquale. A drug used in traditional medicine: Harpagophytum procumbens DC. IV. Effects on some isolated muscle preparations. J Ethnopharmacol. 1985;13(2):201-208. View abstract.

This is significant because when TNF-alpha is overactivated, chronic inflammation can occur and lead to a variety of diseases. In fact, inhibition of TNF-alpha is a major subject of study in the prevention of inflammatory diseases such as rheumatic disease, psoriasis, psoriatic arthritis and inflammatory bowel disease (IBD). ( 19 ) 6. Rich in Antioxidants Medications, such as nonsteroidal anti-inflammatory drugs (NSAIDs), are typically used to reduce pain and swelling caused by gout. You can find devil’s claw supplements in the form of concentrated extracts and capsules, or ground into a fine powder. It’s also used as an ingredient in various herbal teas. Summary Loew, D., Mollerfeld, J., Schrodter, A., Puttkammer, S., and Kaszkin, M. Investigations on the pharmacokinetic properties of Harpagophytum extracts and their effects on eicosanoid biosynthesis in vitro and ex vivo. Clin.Pharmacol.Ther. 2001;69(5):356-364. View abstract. Devil’s claw also contains useful bioflavonoids and phytosterols, which are plant-based antioxidants with antispasmodic properties (which supports the use of this supplement for digestive problems).

Cuspidi C, Sala C, Tadic M, et al. Systemic hypertension induced by Harpagophytum procumbens (devil's claw): a case report. J Clin Hypertens (Greenwich) 2015;17(11):908-10. View abstract. an NSAID--aspirin, ibuprofen (Advil, Motrin), naproxen (Aleve), celecoxib, diclofenac, indomethacin, meloxicam, and others.

In addition to reducing pain, it’s possible that devil’s claw benefits arthritis sufferers by preventing bone loss. Although tests thus far have taken place only in lab and animal tests, there are promising results that suggest devil’s claw prohibits bone loss in inflammatory osteoporosis. ( 10 ) These results are conflicting when it comes to hormonally activated osteoarthritis. ( 11 ) 2. Might Aid in Weight Loss Tunmann P and Lux R. Zur Kenntnis der Inhaltsstoffe aus der Wurzel von Harpagophytum procumbens DC. DAZ 1962;102(40):1274-1275.Even if you’re not looking for a pain remedy, you may still be interested to know the other devil’s claw benefits scientists have discovered. For example, there is at least one early report that it may have anticancer potential. In a cancer unit at a hospital in British Columbia, a doctor noticed a partial regression of one patient’s lymphoma after 10 months with no chemotherapy. The patient shared that he was taking two supplements, including devil’s claw. After hearing about this natural treatment, another patient in a support group with the first began taking devil’s claw, followed by a similar regression 11 months later, sustained for four years. Soulimani R, Younos C, Mortier F, Derrieu C. The role of stomachal digestion on the pharmacological activity of plant extracts, using as an example extracts of Harpagophytum procumbens. Can J Physiol Pharmacol 1994;72:1532-6. View abstract.

It’s possible devil’s claw may interact with certain medications. Consult your doctor before starting devil’s claw if you take other medications regularly. Of course, there are also conditions directly characterized by inflammation, such as inflammatory bowel disease (IBD), arthritis and gout ( 10, 11, 12). Fontaine, J., Elchami, A. A., Vanhaelen, M., and Vanhaelen-Fastre, R. [Biological analysis of Harpagophytum procumbens D.C. II. Pharmacological analysis of the effects of harpagoside, harpagide and harpagogenine on the isolated guinea-pig ileum (author's transl)]. J Pharm Belg. 1981;36(5):321-324. View abstract. One high-quality study compared the level of pain improvement in participants randomly selected to receive devil’s claw with that of participants assigned to take phenylbutazone (an non-steroidal anti-inflammatory drug). Participants taking devil’s claw reported fewer side-effects and had slightly better pain improvement. Pinget M and Lecompte A. Etude des effets de I'harpagophytum en rhumatologie dégénérative. 37 Le magazine 1990;(10):1-10.There don’t seem to be any negative side effects of taking devil’s claw. There have been some reports of mild gastrointestinal issues, however. Are there any contraindications when taking devil’s claw? Baghdikian B, Lanhers MC, Fleurentin J, et al. An analytical study, anti-inflammatory and analgesic effects of Harpagophytum procumbens and Harpagophytum zeyheri. Planta Med 1997;63:171-6. View abstract. Versus Arthritis, the UK’s leading arthritis research charity, says ‘evidence suggests that devil’s claw may be as effective as conventional medicines for osteoarthritis. 10

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